Search results for "heavy [boson]"
showing 10 items of 52 documents
Generation of reporter plasmids containing defined base modifications in the DNA strand of choice
2012
Physiological effects of DNA bases other than A, G, C, and T as well as ways of removal of such bases from genomes are studied intensely. Methods for targeted insertion of modified bases into DNA, therefore, are highly demanded in the fields of DNA repair and epigenetics. This article describes efficient procedures for incorporation of modified DNA bases into a plasmid-borne enhanced green fluorescent protein (EGFP) gene. The procedure exploits excision of a stretch of 18 nt from either the transcribed or nontranscribed DNA strand with the help of the sequence-specific nicking endonucleases Nb.Bpu10I and Nt.Bpu10I. The excised single-stranded oligonucleotide is then swapped for a synthetic …
Ville et fortifications : de l'héritage à la production du territoire urbain
2015
A large number of french cities host military historical edifices (citadels, barracks, bastions, defensive walls, etc.). Although their initial defensive functions have been lost over time, these edifices remain deeply rooted in the urban fabric of their host cities. They continue exerting an impact on these cities’ urban morphology and modern-time functions as well as the way in which the concept of city is understood. Cities nowadays face some new challenges,the increasing awareness of urban sprawl and its consequences, coupled with an urge to promote a renewed and sustainable urbanism, invites us to adopt new approaches to study urban fortifications. In addition to their symbolic aspect,…
The study of neutron-rich nuclei production in the region of the closed shell N=126 in the multi-nucleon transfer reaction 136Xe+208Pb
2015
Expérience LNL/PRISMA; International audience; The unexplored area of heavy neutron rich nuclei is extremely important for nuclearastrophysics investigations and, in particular, for the understanding of the r-process ofastrophysical nucleogenesis. For the production of heavy neutron rich nuclei located along theneutron closed shell N=126 (probably the last "waiting point" in the r-process of nucleosynthesis)the low-energy multi-nucleon transfer reaction 136Xe+208Pb at Elab=870MeV was explored.Due to the stabilizing eect of the closed neutron shells in both nuclei, N=82 and N=126, andthe rather favorable proton transfer from lead to xenon, the light fragments formed in this processare well b…
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
2010
Contains fulltext : 89305.pdf (Publisher’s version ) (Closed access) Smoking is a common risk factor for many diseases. We conducted genome-wide association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers (n = 31,266) and smoking initiation (n = 46,481) using samples from the ENGAGE Consortium. In a second stage, we tested selected SNPs with in silico replication in the Tobacco and Genetics (TAG) and Glaxo Smith Kline (Ox-GSK) consortia cohorts (n = 45,691 smokers) and assessed some of those in a third sample of European ancestry (n = 9,040). Variants in three genomic regions associated with CPD (P < 5 x 10(-8)), including previously identified SNPs at 15q25 repre…
TREATMENT OF PERSISTENTLY OPEN MACULAR HOLES WITH HEAVY SILICONE OIL (DENSIRON 68) VERSUS C2F6. A PROSPECTIVE RANDOMIZED STUDY
2016
Abstract PURPOSE: To compare the efficacy of a mixture of silicone oil and perfluorohexyloctane (Densiron 68) with C2F6 gas endotamponade in the retreatment of persistently open full-thickness macular holes. METHODS: In this prospective randomized study, 21 consecutive patients who were unsuccessfully operated on for large idiopathic full-thickness macular hole were randomly assigned to undergo a second vitrectomy with 20% perfluoroethane gas (C2F6, Group A) or with Densiron 68 tamponade (Group B). PRIMARY OUTCOMES: Endpoint (12 months) full-thickness macular hole closure rate by spectral domain optical coherence tomography and logMAR corrected distance visual acuity. SECONDARY OUTCOMES: po…
Relativistic Energy Density Functional Description of Shape Transition in Superheavy Nuclei
2012
Relativistic energy density functionals (REDF) provide a complete and accurate, global description of nuclear structure phenomena. A modern semi-empirical functional, adjusted to the nuclear matter equation of state and to empirical masses of deformed nuclei, is applied to studies of shapes of superheavy nuclei. The theoretical framework is tested in a comparison of calculated masses, quadrupole deformations, and potential energy barriers to available data on actinide isotopes. Self-consistent mean-field calculations predict a variety of spherical, axial and triaxial shapes of long-lived superheavy nuclei, and their alpha-decay energies and half-lives are compared to data. A microscopic, RE…
Flavour in heavy neutrino searches at the LHC
2012
Heavy neutrinos at the TeV scale have been searched for at the LHC in the context of left-right models, under the assumption that they couple to the electron, the muon, or both. We show that current searches are also sensitive to heavy neutrinos coupling predominantly to the tau lepton, and present limits can significantly constrain the parameter space of general flavour mixing.
Light baryons and their electromagnetic interactions in the covariant constituent quark model
2012
We extend the confined covariant constituent quark model that was previously developed by us for mesons to the baryon sector. In our numerical calculation we use the same values for the constituent quark masses and the infrared cutoff as have been previously used in the meson sector. In a first application we describe the static properties of the proton and neutron, and the $\Lambda$-hyperon (magnetic moments and charge radii) and the behavior of the nucleon form factors at low momentum transfers. We discuss in some detail the conservation of gauge invariance of the electromagnetic transition matrix elements in the presence of a nonlocal coupling of the baryons to the three constituent quar…
Search for K+ decays to a muon and invisible particles
2021
The NA62 experiment at CERN reports searches for $K^+\to\mu^+N$ and $K^+\to\mu^+\nu X$ decays, where $N$ and $X$ are massive invisible particles, using the 2016-2018 data set. The $N$ particle is assumed to be a heavy neutral lepton, and the results are expressed as upper limits of ${\cal O}(10^{-8})$ of the neutrino mixing parameter $|U_{\mu4}|^2$ for $N$ masses in the range 200-384 MeV/$c^2$ and lifetime exceeding 50 ns. The $X$ particle is considered a scalar or vector hidden sector mediator decaying to an invisible final state, and upper limits of the decay branching fraction for $X$ masses in the range 10-370 MeV/$c^2$ are reported for the first time, ranging from ${\cal O}(10^{-5})$ t…
Heavy neutrino searches at the lhc with displaced vertices
2013
Sterile neutrinos with masses in the range (1-100) GeV, have been searched for in a variety of experiments. Here, we discuss the prospects to search for sterile neutrinos at the LHC using displaced vertices. Two different cases are discussed: (i) the standard model extended with sterile neutrinos and (ii) right-handed neutrinos in a left-right symmetric extension of the standard model. A dedicated displaced vertex search will allow to probe parts of the parameter space not accessible to other searches, but will require large luminosity in both cases.